Reuters list of Top 16 Hollywood Celebrity breakups this year 2012,
Katie Holmes filed for divorce from husband Tom Cruise in June. The couple had been married since 2006.
Justin Bieber and Selena Gomez broke up in November according to media reports. The two had been dating publicly since February 2011.
Russell Crowe and wife Danielle Spencer split in October. The couple had been married since April 2003.
Amy Poehler and husband Will Arnett separated in September after nine years of marriage.
Heidi Klum and husband Seal announced they were separating in January after seven years of marriage.
Danica Patrick and husband Paul Hospenthal announced they were divorcing in November after seven years of marriage.
Maroon 5 singer Adam Levine and Victoria's Secret model Anne Vyalitsyna split in April.
Peter Facinelli and wife Jennie Garth split in March after eleven years of marriage.
Johnny Depp and Vanessa Paradis split in June after fourteen years.
Dennis Quaid and wife Kimberly Buffington separated in September after eight years of marriage.
Djimon Hounsou and Kimora Lee Simons split in November after five years together.
Ashlee Simpson and actor Vincent Piazza broke up over the Thanksgiving holiday according to media reports. The two had been dating for a year and a half.
Danny DeVito and wife Rhea Perlman separated in October after 30 years of marriage.
Daniel Radcliffe and Rosie Coker broke up in October after over a year and a half of dating. The two met while Coker was working as a production assistant.
Hayden Panettiere and NFL player Scotty McKnight broke up in November.
Joe and Tina Simpson, the parents of Jessica and Ashlee Simpson, divorced in October after 35 years of marriage.